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Good morning from the PacNW,

Have two idea I'd like to include in my game from Charles Stross's: The Laundry Files books.

Kranzberg Syndrome also called K-Syndrome
Medical name: Krantzberg - Godel Spongiform Encephalopathy
Defined as: Neurodegenerative disease that exclusively targets magic practitioners. The idea is that casting blinding/ without help or assistance get the attention of extra dimensional parasitic worms that start eating microscopic holes in your brain. Not so bad at first: numbness, tingling, visibility issues. Long term effects like paralysis, memory loss, and eventually death.

Table-
-Using a proper devise = 0% chance (was made to do that spell or ritual)
-Using a devise not suited =+25-75% (wasn't made to do that spell or ritual, but with some mods/ lets give it a shot)
-Casting below current level = +10% per level
-Casting at current level = 0%
-Casting above current level = -15% per level
-Casting with charms = See details of charms
-Casting on/near ley line or nexus point = +5% per level (descending) Example: Lev 15 = +5%, Lev 10 = +30%, Lev 5 = +80%
-Casting with proper ingredients (if required) = +5% per ingredient
-Casting with out proper ingredients = -10% per ingredient
-Casting ritual magic = 50% +/- 10% per level
-Casting curses or blessings = 50% +/- 25% per level


V-Syndrome (living vampires, v-parasite)
Infections happens during a particular ritual. Infected are not dead, and have parasites that can help them out but at a cost.
Note: PPE pool gets a very flexible on this
Pros:
-Casting magic doesn't infer K-syndrome
-Can bolster stats by spending PPE - Bolstering lasts 1 hr and is 5:1 on the PPE spending
-Can heal by spending PPE (1:3 for HP, and 1:9 for SDC)
-Enhanced Night vis up to 2000 ft
-Heightened senses (note this can be a Con, due to it doesn't turn off)
-SDC x10 from normal state
-Exempt from H2O weakness
Con's:
-Must feed on blood to replace PPE (was thinking ISP as well, but I'm still testing this)
-Feeding causes a link from the parasites to the victim. the parasites act like K-syndrome, and start eating the brain. Some feeding it takes longer, lots of feeding speeds up the process.
-Parasites consumes 10 PPE/day. If the PPE drops too low, the parasites start eating the host. Note: is reversible at 25:1 to get ride of I'm going to say hole tokens for now.
-Both vampire weakness's and mortal weakness's

PPE feeding tables. I'm running this post Dark day, so yes I'm seasoning my BTS-2 with Nightbane
Also when I calculated Normal humans I did so using the PCC: Ordinary Person table
NPC/ PC = current value of PPE.
Animals no mater the size = 10 PPE and its disgusting/ make save vs horror factor for each. Failed save means half of the blood (PPE) is vomited up.
Normal humans: (feeding on humans becomes addicting, the parasite rewards the host during the experience)
-0-12yrs old = 20 + 9 +10 x 2 = 78
-13-19 yrs old = 13 + 9 + 10 x 2 = 64
-20-28 yrs old = 9 + 9 + 10 x 2 = 56
-29 & over = 4 + 9 + 10 x 2 = 32

If feed on till dead, the PPE doubles

So these are my idea on how to use these, let me know what you think.

We don't have official magic rules for the second edition of BTS yet so it's tough to say how that would integrate. I believe BTS vampires rules were published in a Rifter but I'm not sure if they are official.
That being said - looks like some neat ideas. I am only vaguely familiar with The Laundry but I've heard good things. K-syndrome explains why old, solitary mages go nuts and why others gather cults around them. V-syndrome could be an 'alternate' vampire type to go along with the ones that already exist in most Palladium settings - a type of vampire with a few differences to through the party off.